Around 12 people, including five activists of the Muttahida Qaumi Movement (MQM), have been killed in the city since yesterday, police said.
One person was killed and five others injured in a hand grenade attack on a hotel in Quaidabad in Landhi today.
The violence continued throughout the day with two brothers, Asif and Yasin, shot dead in Baldia Town's Gulshan- i-Mazdoor area by unidentified gunmen, while another man also lost his life as gunmen open fired on him in Baldia Town.
In another attack by unknown assailants, a former union councillor belonging to the MQM, Muhammad Khursheed, was shot dead in Saudabad, Malir area.
According to police, two armed men on a bike opened indiscriminate firing on Khursheed, who was also riding a motorbike. Nine bullets hit him, four in head and five in chest, resulting in his instant death.
Moreover, two people were injured in incidents of firing near the Karimabad bridge and near Sea View.
Since last year Karachi has witnessed a series of violence with over 300 people killed this year alone.