Playing their third Grand Slam final together, the seventh seeded Indian pair scored a 7-6 (3) 6-1 win over the Polish-Mexican pair in one hour and 13 minutes at the Court Philippe Chatrier.
It is second career Grand Slam title for Sania while 12th Major trophy for Bhupathi, who now has won eight mixed doubles trophies.
Sania and Bhupathi had won the 2009 Australia Open and it is their first Grand Slam title since then. Sania had become first woman tennis player from India to win a Grand Slam with that Australian Open trophy.
Leander Paes is the most successful Indian tennis player with 13 Grand Slam titles, seven of which are men's doubles trophies with various partners.
With this win, Sania and Bhupathi sent out a warning to the players worldwide that they will be the force to reckon with at the upcoming London Olympics.
However, they are not yet sure of competing there. Sania needs to get the wild card to make the women's singles draw which will make her eligible to contest in the mixed doubles.
In today's match, the Indians were slow off the blocks with their rivals dominating the proceedings early on but they raised the level of their game as the match progressed and in the end scored a comfortable win. More
