"I think the Central Bureau of Investigation has unfortunately become the favourite whipping boy of everybody who is unfortunately on their wrong side," Tewari told reporters on the sidelines of a function here.
He said the people who "politicise" the CBI should take a fundamental call on what their stance is on the efficacy and relevance of the investigative agency.
"I think you need to make that leap of faith and conclusively determine once and for all whether you have faith in the CBI or you do not have faith in CBI," he said.
"Because you cannot have one standard when a CBI investigation suits your political objectives and another standard when it goes in a different direction altogether," the minister said.
Tewari was speaking at a function where the Department of Audio Visual Publicity released a calendar for the year 2013, which highlights schemes of the central government.
When asked to comment on the issue related to torture of Kargil martyr Captain Saurabh Kalia whose father has moved the Supreme Court seeking directions to the government to raise the issue at the International Court of Justice, he said, "His pursuit for justice (is one) with which the government empathises with."
"We do hope that Pakistan also realises the weight of public opinion in India and takes all the steps which are essential to bring the perpetrators to justice," he said.