In a new interview, "The Sweetest Thing" star said she struggled to come to terms with losing both of her breasts, reported Showbizspy.
The 40-year-old also talked about how she was denied the time to grieve, as the media learned about her surgery immediately following the operation.
"I miss my exquisite breasts sometimes. The good thing is that we got the information out, but talking about the facts of the disease, I didn't have to see what was going on with me. I think when it slowed down, all that came crashing down," she said.
Applegate, who welcomed her first child, Sadie Grace, in early 2011, hopes to have another with her partner, but sadly, it may not be an option.
"Because of some things that happened during my pregnancy, I don't know if I can. I hope I can. We'll see," she added.