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Emergence and expansion of variant viral strains of HIV-1

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Press Trust of India Bangalore

The scientists found the emergence and expansion of three to five new strains of the Human Immunodeficiency Virus Type I rapidly replacing the standard viral strain, according to a press release on 'Emergence and expansion of variant viral strains of HIV-1 in India and other global regions'.

The discovery has been published in the Journal of Biological Chemistry by the group led by Prof Ranga Uday Kumar of Molecular Biology and Genetics Unit of JNCASR.

"The study is the first of its kind to identify that a major family of HIV-1 undergoing an evolutionary modification," the JNCASR release said.

The work consisted of an active collaboration with several research institutes and hospitals that specialise in HIV management.

 

The YRG Centre for AIDS Research and Education (YRG CARE), Chennai, St. John's National Academy of Health Sciences, Bangalore, National Institute of Mental Health and Neurological Sciences Bangalore, and the All India Institute of Medical Sciences, New Delhi took part in the research.

Scientists from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, the USA also participated.

"The new viral strains appear to contain a stronger viral promoter," the release stated. (MORE)

  

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First Published: Nov 07 2012 | 6:45 PM IST

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