The fire was reported around 0645 AM from the ground floor of the four-storeyed building and five fire tenders were rushed.
Fire officials said that the fire engulfed the public relations section of the force and a number of books, documents and other material has been destroyed.
There were no report of casualities and the fire has been controlled, they said.
The CRPF headquarters is a fortified building and is located next to the NIC complex in the Central Government Offices (CGO) complex here.
