Ranked 21 in the world, Ghosal got the better of Nandrajog 11-6 11-6 11-7 to set up a last four stage clash against Ravi Dixit of Tamil Nadu.
All the top seeds remained on course in the women's section as India's number one Joshana Chinappa got a walk over after Kiran Katoch of Jammu and Kashmir conceded the match.
Joshana will now take on Vrishrutyi Sahni of Maharashtra, who defeated Janet Vidhi Delhi in another last eight battle.
Results (Quarter-finals):
Men's: Saurav Ghosal (TN) b Gaurav Nandrajog (Del) 11-6 11-6 11-7; Ravi Dixit (TN) b Vikas Jangra (Ser) 9-11 11-6 11-2 11-7; Mahesh Mangaonkar (Mah) b Abhinav Sinha (Mah) 11-3 11-6 11-3; Harinder Pal Sandhu (TN) b Sandeep Jangra (Ser) 12-10 11-9 11-13 11-9.
Women's: Joshana Chinappa (TN) vs Kiran Katoch (J&K), walk-over; Vrishrutyi Sahni (Mah) b Janet Vidhi (Del) 7-11 11-9 5-11 13-11 14-12; Sachika Ingale (Del) b Aishwarya Bhattacharya (Mah) 11-4 11-7 11-4; Anaka Alankamony (TN) b Tamanna (UP) 11-0 11-0 11-2.
