Seeded 12th, Gurusaidutt sailed past Yan Kit Chan of Hong Kong 21-11 21-14 in 34 minutes at the Macau Forum, thereby equalling their head-to-head record to two-all.
The World No.51 Indian, who reached a career high ranking of 37 earlier in February, completely dominated his opponent in the first game riding on his attacking style of play.
Chan tried to forge a comeback in the second game and at one stage was trailing Gurusaidutt 14-16.
But the Indian didn't allow his opponent any room therafeter and pocketed five straight points to seal in his place in the last four round, where he will be up against Chinese World No.65 Yuekun Chen tomorrow.
Srikanth, on the other hand, had a sweat it out against Nan Wei of Hong Kong before registering a 16-21, 21-19, 21-19 victory in one hour and two minutes.
The first game saw a neck-and-neck fight between Srikanth and Wei till 15 points before the World No. 90 shuttler from Hong Kong ran away with the game.
The second and third games also witnessed tough fights between the duo with both games reaching 19-all.
But the World No. 109 Indian, who has climbed more than 200 places in the rankings since the beginning of the season, clinched the final two points in both the games to enter the semi-finals, where he will face another Chinese Huan Gao tomorrow.
However, it was curtains for doubles specialist Ashwini Ponnappa, wh crashed out in the quarter-finals of both mixed and women's doubles competition.
While the duo of Ashwini and Tarun Kona lost 9-21 13-21 against top seeds Tontowi Ahmad and Liliyana Natsir of Indonesia in the mixed doubles event, the pair of Ashwini and Pradnya Gadre went down 16-21 21-12 15-21 to Komala Dewi and Jenna Gozali of Indonesia in the women's doubles competition.
