A rocket took off from Cape Canaveral in Florida on Thursday night carrying Israel's Beresheet spacecraft, aiming to make history twice: as the first private-sector landing on the Moon, and the first from the Jewish state.
The 585-kilogram (1,290-pound) Beresheet, which means "Genesis" in Hebrew, lifted off at 8:45 pm (0145 GMT Friday) atop a Falcon 9 rocket from the private US-based SpaceX company of entrepreneur Elon Musk.
Take-off was followed live back in Israel, with Prime Minister Benjamin Netanyahu watching alongside engineers from the control center of the Israeli Aerospace Industries (IAI).
The Israeli craft has been placed in Earth orbit, from where it will use its own engine to undertake a seven-week trip to reach the Moon and touch down on April 11 in a large plain.
The rocket also contains an Indonesian satellite and a satellite of the US Air Force Research Laboratory.
Up it goes! @TeamSpaceIL's 'Beresheet' (Genesis) moon lander was successfully launched into space, beginning its journey to the moon. A historic moment for Israel's space program!