The upbeat song, which also features rapper Jay-Z, is the 31-year-old's first musical offering since 2006's critically acclaimed 'FutureSex/LoveSounds'. The song is the first release off Timberlake's forthcoming album "The 20/20 Experience".
In a letter posted on his website, Timberlake, who tied the knot recently with actress Jessica Biel, said he began recording music in June.
"Back in June of last year, I quietly started working on what is now, my next journey with that thing I love called music. The inspiration for this really came out of the blue and to be honest, I didn't expect anything out of it. I just went into the studio and started playing around with some sounds and songs.
"It was probably the best time I've had in my career... Just creating with no rules and/or end goal in mind and really enjoying the process," Timberlake wrote on his blog.
Timberlake has co-written and co-produced 'Suit and Tie' with Timbaland, who produced much of the Grammy-winning 'FutureSex/LoveSounds'.
The buzz around the singer's return to music kicked off Friday when he posted a video on his website that showed him walking into a studio, putting on headphones and saying, "I'm ready."