He then sent over the tape to co-star Evan Rachel Wood and asked for pointers, reported MTV News online.
LaBeouf, 26, admitted he was "scared" to a play character who takes the psychedelic drug Lysergic acid diethylamide (LSD), because he'd "never done acid before". So, he decided to try it out for real and film his trip.
"I remember sending Evan tapes. I remember trying to conjure this and sending tapes and Evan being like, 'Yeah, that's good, but that's not, but this is, but that ain't'," said LaBeouf.
"Not like I would know about these drugs!" Wood, 25, who is currently expecting her first child with husband Jamie Bell, interjected.
"Not like she's the expert on set," LaBeouf explained. "I'm just saying you reach out to friends and you sort of gauge where you're at. So I was sending tapes around. I'd get fifty percents from people, and that starts creeping me out, and I got really nervous. Towards the end, I was like..."
"It was spot on," Wood said.
"That's what propels things like that -