He was 77. He is survived by two sons and two daughters.
Thilakan had been battling for life at the hospital where he was admitted on August 23 after he had suffered two heart attacks. He had been on and off ventilator since then and had an attack of pneumonia. The end came at 3.35 am today.
Thilakan who began his acting career in his intermediate days, had been associated with several drama troupes in his early days including the pro-Left Kerala Peoples' Arts Centre (KPAC). He entered the filmdom in 1979 with a minor role in K G George's 'Ulkadal'.
Since then, he had acted in more than 200 films and won several national and state awards. He won the National Award for Best Supporting Actor in 1988.
He had won state awards for best actor thrice. The actor was awarded the 'Padmashree' in 2009.
'Perumthachan,' 'Yavanika,' 'Kireedam,' 'Kannezhuthi Pottum Thottu,' 'Indian Rupee,' 'Moonnampakkam' and 'Kilukkam' are some of the notable films he acted in. 'Ustad Hotel' is his last released film.