In a medical first, a woman in Sweden has given birth after receiving a womb transplant, the doctor who performed the pioneering procedure said today.
The 36-year-old mother received a uterus from a close family friend last year. Her baby boy was born prematurely but healthy last month, and mother and child are now at home and well. The identities of the woman and her male partner were not disclosed.
"The baby is fantastic," said Dr. Mats Brannstrom, a professor of obstetrics and gynecology at the University of Gothenburg and Stockholm IVF who led the research and delivered the baby with the help of his wife, a midwife. "But it is even better to see the joy in the parents and how happy he made them."
Brannstrom said it was "still sinking in that we have actually done it."
The feat opens up a new but still experimental alternative for some of the thousands of women each year who are unable to have children because they lost a uterus to cancer or were born without one.
Before this case proved the concept can work, some experts had questioned whether a transplanted womb would be able to nourish a fetus.
For the proud parents, the years of research and experimentation were well worth the wait.
"It was a pretty tough journey over the years, but we now have the most amazing baby," the father said in a telephone interview. "He is very, very cute, and he doesn't even scream, he just murmurs." He said he and his wife, both competitive athletes, were convinced the procedure would work, despite its experimental nature.
Brannstrom and colleagues transplanted wombs into nine women over the last two years as part of a study, but complications forced removal of two of the organs.
Earlier this year, Brannstrom began transferring embryos into the seven other women. He said there are two other pregnancies at least 25 weeks along.
Before these cases, there had been two attempts to transplant a womb in Saudi Arabia and Turkey but no live births resulted. Doctors in Britain, France, Japan, Turkey and elsewhere are planning to try similar operations, but using wombs from women who have just died rather than live donors.
The Swedish woman had healthy ovaries, but she was born without a uterus a syndrome seen in one girl in 4,500. She received a uterus from a 61-year-old family friend who had gone through menopause after giving birth to two children.
Brannstrom said that he was surprised such an old uterus was so successful, but that the most important factor seemed to be that the womb was healthy.
