Kerala hurdler T.S. Arya (14.81s) and Tamil Nadu athlete Dhanalakshmi Bhaskaran (15.03s) filled the next two places on the podium.
Meghana, who won the gold in Junior Federation Cup in Pune this May and fetched a bronze in the Senior Nationals at Hyderabad last month, however missed the national youth record of 14.02s standing in the name of Tamil Nadu's Gayathri Govindarajan since 2008.
Her coach V.R. Beedu said Meghana is a good prospect to win a medal at the continental level in future.
Minutes after, Fakeerappa V. Bangi brought another gold for Karnataka as he takes the boys' 110m hurdles in 14.51s. His teammate C. Shivakumar (14.91s) got a bronze medal behind Jharkhand