Having taken a massive lead over the visitors, Mumbai went on to pile up 230 for five in their second innings.
Mumbai had scored 570 all out in their first innings.
Resuming at 380 for eight, Railways had a tough task of avoiding the follow on and the overnight batsmen -- Krishnakant Upadhyay (45) and Anureet Singh (30 not out) -- shared a 74-run stand for the ninth wicket to overcome the challenge.
Mumbai's bowling attack without Zaheer Khan, who had left mid-way during one of his overs due to cramps yesterday, seemed lacklustre earlier on.
However, Railways batsmen failed to sustain for long and fell for a little over 420-run mark within 40 minutes of play in the morning session and trailed Mumbai by 144 runs.
Dhawal Kulkarni claimed both the wickets with Upadhyay and Hardik Rathore (0) in his consecutive overs.
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