Eight-time winner Rafael Nadal and four-time finalist Roger Federer will line up against a pair of underpowered hopefuls in the second round of the Monte Carlo Masters
Nadal, who is working to return to his previous best on his longtime favourite surface, will open in the second round after a bye against British number two Aljaz Bedene.
The Slovenian-born world number 60 will face one of the toughest tests on clay when he takes on the Spaniard who dominated with consecutive trophies from 2005-12.
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Nadal has never played Bedene, Federer is 3-0 over Garcia-Lopez as the pair meet for the first time on clay.
Bedene booked his spot against Nadal as he defeated Czech Lukas Rosol 6-2, 6-3 on Monday.
Spaniard Guillermo Garcia-Lopez made it past Brazil's Thomaz Bellucci 7-5, 6-1 to next face third seed Federer, who is set to play his first match in more than two months after a knee procedure.
Nadal is looking for his first title on any surface since last summer and will willingly make 57th-ranked, Slovenia-born Bedene his first victim of the week in the principality.
Federer most recently lost a Monte Carlo final two years ago against compatriot Stan Wawrinka. Bedene appears ready to take up his challenge against the mighty Nadal.
"I'm playing well, at the moment I'm enjoying playing tennis. It's going to be against Rafa, who I respect. He's one of the best clay-courters.
"It's going to be fun, definitely if I bring my best tennis. I'm not the favourite, but I stand a chance. It's never a good time to play someone like him. But if I can pick any, this is the time.