Nalini overcame double bogeys on the front-nine and held her nerve in the closing stages with a birdie and five pars in the last six holes for a card of 75.
Nalini totalled 217, four clear of Smriti Mehra (80) and Vani Kapoor (72), who were tied for second at 221.
It was the season's first win for Nalini, who is coached by Anitya Chand, also the coach for Vani.
"It feels nice to finally win after coming close many times and it becomes even better because this is my home course," said an elated Nalini, who was second last week.
For Vani it was her second runner-up finish and she has one win. In five events, there have been four winners, with only Smriti winning twice.
With Smriti dropping from the top with a horrendous run of three bogeys followed by a quadruple bogey on the par-three 16th, Nalini just had to ensure she made no similar costly mistakes. Smriti ended with an 80 to be in a tie for second with Vani.
Vani who had a stunning three-under 33 on the back nine had the best round on the final day. She could well have pushed Nalini a bit more but for a poor start and then another two bogeys on the back nine. MORE