Benchmark Nifty snapped its 4-day winning run to end 19 points lower today following profit booking in banking and auto stocks.
Weakness in global stocks also weighed on sentiment.
Sustained buying in realty, media, metal and IT counters capped the losses.
Overseas, European and Asian stocks dropped even as the US Senate passed the Republican tax bill in a 51-48 vote, sending the tax cut package back to the House of Representatives for a final vote.
The NSE Nifty opened higher at 10,494.40 and moved in a range of 10,494.45 and 10,437.15, before ending at 10,444.20 down 19 points, or 0.18 per cent from its last close.
It saw an intra-day movement of about 57.30 points.
On the sectoral front, PSU Bank fell by 1.15 per cent, followed by Bank 0.48 per cent, Finance Service 0.44 per cent, Energy 0.35 per cent, Auto 0.32 per cent, Private Bank 0.28 per cent.
However, Realty rose by 2.95 per cent, Media 0.72 per cent, Metal 0.66 per cent, IT 0.57 per cent, Infra 0.22 per cent and FMCG 0.13 per cent.
Major index gainers were Hindalco, ONGC, Wipro, Hero MotoCo, Infosys, L&T, Lupin, Wipro and Bajaj Finance.
Losers included Eicher Motors, Dr Reddy's, Bharti Airtel, Ambuja Cement, HPCL, Mahindra & Mahindra and Tata Steel.
The market breadth, indicating its overall health, was in favour of gainers. On the NSE, 1,064 stocks advanced, 687 declined and 67 remained unchanged.
Total securities that hit their price bands were 171.
Turnover in the cash segment rose to Rs 34,329.08 crore from Rs 31,093.76 crore as on Tuesday.
A total of 19,717.16 lakh shares changed hands in 12,314,401 trades. The market capitalisation of listed firms on the NSE stood at Rs 1,47,24,987.48 crore.
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