Nacer Chadli scored twice as Tottenham Hotspur ensured there was no happy return to White Hart Lane for Harry Redknapp as they beat their former manager's Queens Park Rangers side 4-0 in the Premier League on Sunday.
Sunday's other early kick-off match in the English top-flight saw 10-man Hull draw 1-1 at home to Stoke.
Manchester United will go in search of their first competitive win under manager Louis van Gaal, away to Sunderland, later on Sunday, while reigning champions Manchester City face Liverpool, last season's runners-up, at Eastlands on Monday.
Chadli put Spurs ahead in the 12th minute when he thrashed home Emmanuel Adebayor's cross from six yards out.
Defender Eric Dier doubled Spurs' lead with his second goal in as many matches when he headed in Erik Lamela's corner at the near post on the half hour.
Tottenham went 3-0 up in the 37th minute, the match all but over as contest before half time.
Argentinian playmaker Lamela was again involved, his precise pass finding the head of Chadli, who nodded in from six yards.
Rangers did prevent Spurs adding to their tally until the 65th minute when Togo striker Adebayor side-footed home from six yards out after a fine run and cross by Danny Rose.
Victory meant Spurs went to the top of the table as one of only three sides, with Chelsea and Swansea, to have won both their opening games.
"I am happy to make two goals and help us to the win," said Chadli.
Championship play-off winners QPR -- who have Tottenham great and former England manager Glenn Hoddle working under Redknapp -- have now lost two out of two following their 1-0 loss at home to Hull on the opening weekend.
