While exercise is good for everyone, people with increased risk of type 2 diabetes need to workout more than others to achieve the same results, according to new research.
The cause of type 2 diabetes is linked to both genetics and lifestyle. If you have an immediate relative (mother, father, sibling) with type 2 diabetes, the risk of contracting the diabetes is about three times higher, researchers said.
Preventive treatments involve eating healthier and exercising more.
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The participants consisted of a total of 50 unfit, slightly overweight but completely healthy men in their 40s who, for seven months, exercised regularly at a fitness centre.
Half of them belonged to the risk group and the other half served as a control group who did not have relatives with type 2 diabetes.
The participants were offered three training sessions per week, including a spinning class and two aerobics classes, during which their exercise intensity and energy consumption was measured.
Before and after the exercise period, they individually underwent a medical examination and a glucose tolerance test (sugar load) to study the cells' ability to absorb sugar (glucose) into the blood.
The researchers also performed muscle biopsies on the participants that were analysed to study the activity of various genes.
The exercise routine for both groups was equally hard, but the risk group attended more sessions and as a group expended more energy than the control group.
After making adjustments to account for the differences, the results showed that both groups benefited from exercising; they all lost weight, reduced their waist size and increased their fitness. The genetic analyses also showed similar improvements in the gene expressions in both groups.
"The difference was that participants from the risk group had to exercise more to achieve the same results as the participants from the control group," said Ola Hansson, who led the study.