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Plant compound can prevent growth of breast tumours: study

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Press Trust of India Washington

Researchers from the University of Pittsburgh Cancer Institute found that a plant compound PEITC can hinder the development of mammary tumours in a mouse model with similarities to human breast cancer progression.

Edible plants are gaining ground as chemopreventative agents. PEITC has shown to be effective as a chemopreventative agent in mice for colon, intestinal, and prostate cancer, by inducing apoptosis, the process of programmed cell death in multicellular organisms.

Shivendra V Singh from the University of Pittsburgh Cancer Institute and colleagues placed mice on two diets- a control diet, and a diet supplemented with PEITC for 29 weeks.

The researchers found that administering PEITC for 29 weeks was linked with a 56.3 per cent reduction in mammary carcinoma lesions greater than 2 mm.

 

"Although PEITC administration does not confer complete protection against mammary carcinogenesis, mice placed on the PEITC-supplemented diet, compared with mice placed on the control diet, clearly exhibited suppression of carcinoma progression," the researchers said in a statement.

The study was published in the Journal of the National Cancer Institute.

  

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First Published: Aug 03 2012 | 3:36 PM IST

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