Siddle is among eight Australian players who left for India today. The rest of the nine players will depart on Saturday and Monday after the ongoing limited-overs series against the West Indies.
Talking about the team's batsmen, Siddle said opener Phil Hughes will have a huge role to play.
"If we look at Phillip Hughes, the form he's had since he came back into the Australian side, he showed he'd changed his game for the best," Siddle told reporters here before the departure.
"His form in the one-dayers has been outstanding. If he can translate that over to the Indian conditions, which will be a little bit different, he's the one.
"If he can get going and support Pup (Michael Clarke) and Davy (David Warner) and Watto (Shane Watson) we can get those big totals," he said.
Talking about Australia's old nemesis, Sachin Tendulkar, Siddle said his team would be on its guard against the senior batsman.
"He's finished up one-day cricket and Twenty20 to concentrate on Tests so he'll be looking to come out hard," Siddle said.
"The last series over in Australia we got on top of him a bit but he'll be looking to fire back. He's going to be a tough contest but hopefully one we can get early enough more times than not," he said.