"It reflects very poorly on a candidate who is aspiring to the topmost office of the country," the National Platform for the Rights of the Disabled said in a statement.
Sangma had told reporters in Ahmedabad yesterday that "India should have a President, who is not blind, dumb and deaf. India should have a thinking and a functional President."
The organisation also sought an apology from Sangma for his "insulting" remarks.
"It is unbecoming of a person contesting to become the first citizen of the country to express such insensitivity and callousness, even while lashing out at his rival. In a sweeping remark, the presidential aspirant has deemed persons with disabilities as being unfit to hold the office of the President," the statement said.