The 30-share index, which gained 226.37 points in the previous session, fell by 101.65 points, or 0.58 per cent, to 17,516.70 with stocks of FMCG, auto, realty and oil and gas sectors succumbing to profit-booking.
Similarly, the wide-based National Stock Exchange index Nifty declined by 29.00 points, or 0.54 per cent, to 5,316.35.
Brokers said profit-booking by speculators after yesterday's strong gains and a weak trend on Asian bourses following overnight losses in the US markets amid renewed worries over eurozone efforts to stem the debt crisis, led to a fall in the domestic market.
Meanwhile, in Asian region, Japan's Nikkei Index fell by 0.48 per cent, while Hong Kong's Hang Seng shed 0.13 per cent. The US Dow Jones Industrial Average ended 0.65 per cent lower in yesterday's trade.