The 30-share barometer fell by 88.49 points, or 0.44 per cent, to 19,662.70. The index had lost nearly 254 points in the past three sessions.
Stocks of realty, capital goods, metal, auto, power and banking sectors declined due to profit-booking.
Similarly, the wide-based National Stock Exchange index Nifty fell by 39.35 points, or 0.65 per cent, to 5,947.90.
Brokers said a weak trend in the Asian trade following overnight losses on the US market on weak data, spurring selling, dampened the trading sentiment here.
In the Asian region, Japan's Nikkei Index was down 1.27 per cent, while Hong Kong's Hang Seng index shed 1.66 per cent in early trade.
The US Dow Jones Industrial Average ended 0.93 per cent down in yesterday's trade.
