The 30-share barometer, which gained nearly 455 points in the last four sessions, declined by 89.40 points, or 0.50 per cent, to 17,677.38 with metal, banking and capital goods stocks leading the fall.
Similarly, the wide-based National Stock Exchange index Nifty fell by 31.35 points, or 0.58 per cent, to 5,332.10.
Brokers said fresh selling by funds and retail investors, mostly of a profit-booking nature, and a weakening on Asian bourses influenced the trading sentiment.
Besides, a cautious approach adopted by participants ahead of IIP data to be released tomorrow also impacted the trading sentiments, they said.
In Asian region, Hong Kong's Hang Seng index eased by 0.53 per cent, while Japan's Nikkei shed 0.80 per cent in the opening trade today.
The US Dow Jones had ended 0.39 per lower in yesterday's trade.
