The 30-share barometer, which has gained 75.71 points yesterday, fell by 20.43 points, or 0.12 per cent, to 17,613.02, with stocks of realty, capital goods and healthcare sectors falling on profit-booking.
Similarly, the wide-based National Stock Exchange index Nifty fell by 8.30 points, or 0.16 per cent, to 5,339.60.
Brokers said besides profit-booking after yesterday's gains, cautious approach adopted by participants ahead of the July inflation numbers to be released later today, mainly influenced the trading sentiments.
They, however, said a better trend in the Asian region limited the losses here.
In Asian region, Hong Kong's Hang Seng index was up by 0.85 per cent, while Japan's Nikkei Index rose 0.52 per cent.
The US Dow Jones Industrial Average had ended 0.29 per cent lower in yesterday's trade.
