Shukla will remain in India and not travel to South Africa with the Knight Riders squad as he has to attend to a family illness.
The CLT20 technical committee has allowed KKR to replace Shukla with Das, a 26-year-old middle-order batsman who played eight matches for KKR during their IPL title-winning season this year.
KKR will open their campaign with a match against Delhi Daredevils at Centurion on October 13.
