The white BMW M3 was wrecked when it hit the Tunnel yesterday at an estimated speed of 177kph, four times higher than the tunnel's speed limit of 40kph, Shanghai Daily reported.
The driver, Yu Ji, had a miraculous escape and was not seriously hurt as he was wearing the seat belt.
Police ruled out drunk driving by Yu and said the cause of the accident was still under investigation.
Chen Nanyang (26) was thrown from the car with his girlfriend. Both died at the scene, police said.
Chen's younger sister, Chen Rui, was rushed to a hospital nearby but was pronounced dead.
The white BMW M3 was going an estimated 140 to 180 kilometres per hour in the tunnel, and when it crashed its speed was going 177kph, police said.
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"We were celebrating Chen's birthday overnight and when I got the call I thought it was just a small scratch or something," said a man surnamed Xia, a friend who was at the club and rushed to the tunnel.
"I knew it's all over when I arrived and saw the scene."