Three women were killed after a high-tension electricity wire fell on the bus in which they were travelling near Umaria village under Jaithari police station limits in the district.
Twelve other passengers sustained burn injuries, sub divisional officer of police JBS Chandel said.
The bus was on its way to Seoni from Anuppur.
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The deceased women were identified as Urmila (46), Duyanti (28) and Rupa (50).
The injured persons were admitted in hospitals at Jaithari and Anuppur, the SDOP said, adding a case had been registered.