Cruise, 50, who is said to be desperate for some peace after his split from wife Katie Holmes, 33, in June, has been eyeing on a medieval castle 100 miles north of Rome, reported Sun online.
Clooney, 51, is also keen for Cruise to move into his Villa Oleandra on the shores of Lake Como as he is reportedly looking to switch his holiday home to Salerno in the south of Italy because girlfriend Stacy Keibler is not a fan of the lakes near Milan.
The two actors are thought to be in talks to "strike a deal" on the property.
"Mission Impossible" star is also looking for a home in New York to be closer to his daughter Suri.
