In a show of strength, warships from the US, China and 10 other countries are participating in a five-day war-game hosted by the Pakistan Navy to deter terrorism and piracy in the North Arabian Sea.
The Aman-13 exercise, which began in the Arabian Sea on Monday, involves warships from 12 countries and observers from more than 20 others.
One of the main objectives of the wargame is to "display united resolve against terrorism and crimes in the maritime domain", the Pakistan Navy said in a statement.
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The exercise, being held for the fourth time since 2007, will help develop tactics and procedures as well as improve cooperation between the navies, the statement said.
Rear Admiral Khan Hasham Bin Saddique, the Commander of the Pakistan Navy fleet, said the use of sea routes for terrorism, human trafficking, smuggling and piracy are major concerns.
"We need to make collective efforts to eliminate these for lasting peace in the region," he told the media earlier this week.
Shipping lanes in the Indian Ocean have been plagued by attacks by Somali pirates, who have hijacked dozens of ships and earned millions of dollars in ransom for their release.
"All the nations participating in Aman-13 have a common objective of ensuring peace and stability in the maritime arena to provide freedom of navigation and uninterrupted flow of trade," the Pakistan Navy statement said.
The US Navy has sent the USS William P Lawrence, a Arleigh Burke-class destroyer, to participate in the multinational exercise.
Other countries that have sent warships include Australia, Bangladesh, China, Japan, Sri Lanka and Turkey.
Among the countries that have sent observers are Brazil, Canada, Egypt, Germany, the Maldives, Myanmar, Russia and Saudi Arabia.