The movie will be directed by Rob Reiner. Ford is expected to star as a psychiatrist who faces difficulties after one of his female patients commits suicide, reported Aceshowbiz.
Efron, meanwhile, is poised to tackle the part of the patient's brother James. The psychiatrist and James end up developing a bond, but things turn ugly as James starts seducing the psychiatrist's wife and daughter.
David Murray provides the script and serving as the producers are Richard Lewis, Alan Greinsman and Mark Damon.
The project is targeted to kick off the production in March 2013.