By Hideyuki Sano and Nichola Saminather
TOKYO/SINGAPORE (Reuters) - Asian shares advanced on Friday as investors looked to U.S. employment data that could add to or detract from the case for a Federal Reserve interest rate hike this month or in July.
MSCI's broadest index of Asia-Pacific shares outside Japan was up 0.4 percent, setting it up for a rise of 0.3 percent for the week. Japan's Nikkei gained 0.2 percent, paring losses for the week to 1.5 percent.
Chinese shares were mixed, with the CSI 300 index little changed, while the Shanghai Composite slipped 0.2 percent, putting both on track for weekly gains of about 3.5 percent.
Hong Kong's Hang Seng index climbed 0.3 percent, set for an advance of 1.7 percent for the week.
Markets expect U.S. employment data due at 1230 GMT to show a non-farm payroll increase of about 164,000 and 0.2 percent rise in average wage earnings in May.
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The data will be followed by a speech from Federal Reserve Chair Janet Yellen on Monday, the last chance for the Fed to communicate with markets before it begins a blackout period ahead of its policy meeting on June 14-15.
"If we see a job figure that is largely in line with market consensus and if Yellen maintains a positive tone on rate hikes, I think the chance of a rate hike in June is pretty high," said Masahiro Ichikawa, senior strategist at Sumitomo Mitsui Asset Management.
Currently U.S. money market futures are pricing in only about 20 percent chance of a hike in June and 60 percent by July.
Ahead of the two key events, Wall Street shares held firm, with the S&P 500 gaining 0.28 percent to 2,105.26, mostly led by 1.3 percent rises in the healthcare sector.
It now only needs to rise about 1 percent to set a closing record.
In recent weeks global markets have been puzzling over what the Fed will do in the near term as relatively upbeat U.S. data have been eclipsed by a still-sluggish global economy and worries over the risk of Britain exiting the European Union.
"Markets are pricing in smaller chances of a hike partly because of worries about 'Brexit'. That is also something that could influence the Fed," Ichikawa added.
The uncertain global backdrop was underlined by the European Central Bank, which on Thursday predicted consumer price growth would remain below target through 2018 as it struggles with cheap energy feeding into the price of other goods and services.
The ECB kept its negative rates unchanged, with President Mario Draghi saying stimulus from previously approved and yet to be implemented measures were expected to work its way through the system.
German debt yield hit a three-week low of 0.109 percent on Thursday after the ECB gave a cautious economic outlook.
The euro was little changed at $1.115 on Friday, after sliding from this week's high of $1.1221 touched early on Thursday.
Against the yen, it last stood at 121.38 after falling to a three-year low of 121.065 yen in the previous session.
The yen held steady at 108.915 per dollar, after hitting a two-week high of 108.525 on Thursday, a move some market players attributed to disappointment over a lack of a clear plan on stimulus from Japanese Prime Minister Shinzo Abe. It is poised for a gain of 1.3 percent for the week.
The yen tends to strengthen when there is bad news on the economy because it is often used as a funding currency for investment in higher-yielding riskier assets.
The dollar index, which tracks the greenback against a basket of six major peers, was flat at 95.565.
Oil prices were supported, with international benchmark Brent futures continuing to trade above the $50 a barrel level seen on Thursday for the first time in seven months, after the latest drawdown in U.S. crude stockpiles offset OPEC's failure to set a ceiling for its output.
Brent was steady at $50.10, headed for a rise of 1.6 percent for the week.
U.S. West Texas Intermediate (WTI) crude futures was also flat at $49.19 a barrel. It had tumbled more than $1 earlier in the week, which set it up for a loss of 0.3 percent for the week.
OPEC failed to agree on a clear oil-output strategy on Thursday as Iran insisted on steeply raising its own production, although Saudi Arabia's new oil minister promised not to flood the market and sought to mend fences within the organisation.
(Editing by Shri Navaratnam)