Shares of Facebook Inc
The stock touched $45 at 1:50 pm ET and briefly hit $45.07 shortly after 2 pm on the Nasdaq - highs not seen since May 18, 2012, the day of Facebook's initial public offering. It closed at $45.04.
CEO Mark Zuckerberg is expected to speak later Wednesday at the Techcrunch Disrupt conference in San Francisco.
JMP Securities analyst Ronald Josey said investors expect Zuckerberg to discuss future video ad products as well as plans to make money from its Instagram unit. The mobile photo app, acquired in 2012 by Facebook, is popular with young people but does not carry any advertising.
The stock's new intraday high is the latest milestone in its year-long recovery from fears that Facebook would struggle to make money from mobile users at a time when young people go online mostly through their smartphones.
The sentiment changed completely on July 24 when Facebook said its mobile advertising revenue grew 75% in the second quarter, trouncing analyst targets and delivering the company's strongest revenue growth since the third quarter of 2011.
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The stock has risen 67% since then.
"The second quarter was the turning point when a lot of their work over the last year with the newsfeed came through," Josey said, referring to the format of Facebook updates that also carry mobile ads.
"Mobile is very hard to get audience at scale and Facebook is proving that it's one of those places where advertisers can go to reach eyeballs."
Facebook has said it expects sales and user growth for its mobile apps to outpace its desktop website.
Facebook options also traded heavily on Wednesday.
A total of 317,000 calls and 131,000 puts in Facebook changed hands on Wednesday, above its recent combined daily average of 355,000 contracts, according to options analytics firm Trade Alert.
The weekly $45 strike calls expiring this Friday as well as the September $44 and October $45 strike calls are among the busiest options.
"But one play in the options market appears to be making a 'cheap' bet that the recent run higher is overdone," said WhatsTrading.com options strategist Frederic Ruffy.
The top trade on Facebook on Wednesday was a 10,250-lot of September $39 strike puts, which were bought for 7 cents per contract as a new position. The contract, which is out-of-the-money, expires at the end of next week and would be profitable if shares fall below $38.93, Ruffy said.