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Wall Street edged lower on Wednesday as brewing tensions between the United States and Russia over a possible military action against Syria turned investors risk averse.
The S&P banks index slipped more than 1 per cent and were the biggest decliners. JP Morgan and Bank of America fell about 1.2 per cent, while Goldman Sachs dropped 1.6 per cent.
The US 10-year yields fell to 2.7753 per cent after US President Donald Trump declared that missiles "will be coming" and blasted Moscow for standing by Syrian President Bashar Assad.
Russia had earlier warned that any US missiles fired at Syria over a suspected chemical weapons attack on a rebel enclave would be shot down.
"It feels like there are expectations that the US is going to take some action against Syria, The market, I don't believe, has priced one yet," said Phil Blancato, Chief Executive of Ladenburg Thalmann Asset Management in New York.
At 11:21 am ET, the Dow Jones Industrial Average was down 0.79 percent at 24,216.22. The S&P 500 fell 0.45 percent to 2,644.87 and the Nasdaq Composite declined 0.2 per cent to 7,080.36.
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Financial markets had gained ground after Chinese President Xi Jinping on Tuesday tried to defuse trade tensions with the United States by promising to lower import tariffs.
"You've got the tariff story which continues to proliferate, some of the long-time folks in Congress are stepping down and not willing to run again, and then you've got Syrian issue," said Blancato.
US House of Representatives Speaker Paul Ryan, just months ahead of pivotal congressional elections, said he will not seek re-election to Congress in November and will relinquish his leadership post at the start of 2019.
Data showing a rise in US core inflation for March - which was up 0.2 per cent and matched February's increase rise - failed to boost yields as headline consumer prices fell for the first time in 10 months.
The Federal Reserve is set to release the minutes of its March meeting, when the US central bank voted to raise interest rates.
Escalating tensions in Syria lifted oil prices by over 2 per cent to their highest in more than three years.
Among stocks, Hilton Worldwide jumped 4 percent after the hotel operator's main shareholder HNA Tourism Group decided to sell its stake in the company.
Facebook Inc shares slipped as Chief Executive Mark Zuckerberg started his second day of testimony on Capitol Hill, facing more questions from lawmakers about data privacy at the world's largest social media network.
Declining issues outnumbered advancers on the NYSE for a 1.00-to-1 and on the Nasdaq for a 1.05-to-1 ratio.
