Cancer

Aiims in process of making low cost therapy for treating multiple myeloma

Doctors at AIIMS, Delhi are in the process of developing a low cost antibody-based adaptive cellular therapy for treatment of multiple myeloma, a form of blood cancer. This kind of therapy is expected to make advanced treatments like CAR-T cell therapies more affordable and accessible for patients in India. The Chimeric antigen receptor (CAR) T-cell therapy is a form of adaptive cellular therapy in which a patient's T cells are isolated, genetically modified and infused back in the patients body to recognise and kill the cancer cells, said Dr Mayank Singh, Additional Professor in the Department of Medical Oncology at Dr B R Ambedkar Institute Rotary Cancer Hospital, (BRAIRCH), AIIMS here. It is based on targeting B-cell maturation antigen (BCMA) which helps to target specific tumour antigens which are found cancer cells specially in cases multiple myeloma. "So the therapy developed by the AIIMS researchers recognises BCMA as a target on multiple myeloma cells to eliminate them," Si

IGI's new drug ISB 2001 shows promise in treating multiple Myeloma

The drug is designed to treat a type of blood cancer - relapsed or refractory multiple myeloma - in patients who haven't responded well to other treatments

Delhi HC rejects plea against Navjot Sidhu on wife's cancer cure claim

Observing there still was freedom of speech in the country, the Delhi High Court on Wednesday refused to entertain a plea against Congress leader Navjot Singh Sidhu's claims that certain remedies helped his wife in her battle against stage 4 cancer. A bench of Chief Justice Manmohan and Justice Tushar Rao Gedela said the former cricketer had only voiced his opinion and the petitioner was also free to counter the claims. "He is just voicing his opinion. Counter his claims by holding a press conference. Counter free speech by free speech and not by curtailing his free speech under the fear of legal action or contempt. We still have freedom of speech in this country," the bench said. The bench went on to underline, "You can't say freedom of speech be curtailed. You counter his claim. This is not our domain. If you don't agree with this gentleman's views, don't listen to him. There are a lot of books which you may feel are bad, don't read them. Who is asking you to read them? Free speec

We must strengthen national, int'l collaboration in research: Mukesh Ambani

Mukesh Ambani said that early detection is half the battle won in the fight against cancer at an event in Bengaluru

Study shows severe Covid infection may shrink cancer tumours in mice

The implications of this study extend beyond COVID and cancer. It shows how our immune system can be trained by one type of threat to become more effectiCancerve against another

Lifestyle changes, lack of screening behind rise in breast cancer cases

The data also suggests that states such as Uttar Pradesh, Maharashtra, and West Bengal had the highest incidences of breast cancer in 2023

Immunotherapy was meant to defeat cancer but what happened to great promise

This works because cancers have fooled the body by using its own natural safety switches, or checkpoints

Hollywood Producer Weinstein diagnosed with rare form of bone marrow cancer

Producer Harvey Weinstein, who became synonymous with Hollywood's 2018 #MeToo campaign, has been diagnosed with cancer. Weinstein has chronic myeloid leukaemia and is undergoing treatment while still in prison at Rikers Island in New York, reported NBC News. According to the Mayo Clinic, chronic myeloid leukaemia is an uncommon form of cancer of the bone marrow. The news of Weinstein's cancer diagnosis came after he underwent an emergency heart surgery last month, and tested positive for COVID and double pneumonia in July. Weinstein is currently lodged at Rikers Island as he awaits a retrial in November after his 2020 rape conviction in New York, and 23-year sentence, was overturned in April. He was also indicted on further sexual assault charges in New York last month. He has pleaded not guilty and is now charged under two indictments for three sex crimes. He is expected to be arraigned at a later date. Weinstein didn't appear in court when the details of the indictment were ...

Study shows bacterial vaccine may serve as cancer immunotherapy treatment

The bacterial vaccine proved to be particularly more efficacious than peptide-based therapeutic cancer vaccines

Breast cancer in India: 16% of women aged 55-64 face the silent threat

The rise in breast cancer cases has been linked to various factors, including late pregnancies, family history, hormonal changes, and lifestyle habits like smoking and high stress

ICMR predicts surge in cancer cases between 2022 and 2045 in BRICS nations

Cancer cases in India to surge in India, especially mouth cancer among men and breast cancer among women, reveals ICMR study on BRICS countries

Cancer-causing agents in cakes: Check out some healthier alternatives

Several carcinogenic substances were found in 12 cake samples collected from different Bengaluru bakeries. Here are some healthy alternatives to meet your craving

Ovarian cancer cure? Oxford's vaccine could stop it before it even starts

OvarianVax, a promising cancer vaccine, is in early development as researchers identify proteins on ovarian cancer cells that trigger immune responses

Zydus Lifesciences receives USFDA approval to produce prostrate cancer drug

Zydus Lifesciences on Wednesday said it has received approval from the US health regulator to produce a generic prostate cancer treatment drug. The company has received tentative approval from the US Food and Drug Administration (USFDA) to manufacture Enzalutamide tablets (40 mg and 80 mg), the drug maker said in a regulatory filing. Enzalutamide tablets are androgen receptor inhibitors indicated for the treatment of patients with castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer. The product would be manufactured at the Group's manufacturing site at SEZ, Ahmedabad. As per IQVIA MAT July 2024 data, Enzalutamide tablets (40 mg and 80 mg) had annual sales of USD 1,417.2 million in the US. The Zydus group now has 400 approvals and has so far filed over 465 Abbreviated New Drug Application (ANDAs) since the commencement of the filing process in FY 2003-04, it said.

Sun Pharma signs licensing pact with Philogen for cancer medication

Sun Pharmaceutical Industries on Tuesday said it has inked a global licensing pact with Italian-Swiss firm Philogen for an anti-cancer drug. As per the agreement, Sun Pharma will have the exclusive worldwide rights to commercialise Fibromun, a speciality product of Philogen. Fibromun, an innovative anti-cancer immunotherapy, is being investigated in registration trials by Philogen for the treatment of soft tissue sarcoma and glioblastoma. As per the pact, Philogen will complete the ongoing pivotal clinical trials for the product, pursue marketing authorisation with regulatory authorities, and manufacture commercial supplies, the Mumbai-based drug major said in a statement. Sun Pharma will be responsible for commercialisation activities, it added. The two partner companies will share post-commercialisation economics in about 45(Philogen):55(Sun Pharma) ratio, Sun Pharma said. The company did not disclose other financial terms. "Fibromun's progress through development has been qui

J&J raises baby powder settlement offer to more than $8.2 billion

J&J recently garnered support from more than 75 per cent of baby powder claimants for an out-of-court deal that includes claims that the talc-based version caused ovarian and other gynecological cance

J&J gets $260 million talc verdict overturned in Oregon, new trial ordered

J&J is facing claims by more than 62,000 plaintiffs that its baby powder and other talc products were contaminated with asbestos and caused cancer

Obesity-linked cancer rates surge in China; young adults most affected

From 2007 to 2021, obesity-related cancer rates in China rose by 3.6% annually, with a striking 15.3% increase for those aged 25 to 29, while rates for non-obesity-linked cancers stayed stable

Crucial to focus on cancers unique to low, middle-income nations: US expert

Low and middle-income countries are grappling with dual burden of non-communicable diseases and infection ailments, and it is crucial to "direct more attention" towards cancers prevalent or unique to such countries, a US-based cancer expert has said. Citing data, Dr Shobha Krishnan also said that as cancer cases in India are projected to rise by nearly 13 per cent by 2025 compared to 2020, the "urgency to exchange knowledge and best practices is critical". Krishnan, founder and president of US-based Global Initiative Against HPV and Cervical Cancer (GIAHC), was in India recently to take part in the first-ever US-India cancer dialogue held in Delhi earlier this month. In June 2023, President Joe Biden and Prime Minister Narendra Modi had reaffirmed the strong health partnership between the US and India by announcing new commitments to accelerate the fight against cancer, including convening a US-India cancer dialogue to advance the prevention, early detection, and treatment of ...

World Lung Cancer Day 2024: Know history, significance, theme and more

Lung cancer happens when the cancer cells start developing in the lungs. To spread awareness among people, World Lung Cancer Day is observed every year on August 1