Researchers have discovered an antibody that could counter all known variants of the coronavirus that causes COVID-19 and also distantly related ones that infect other animals. SARS-CoV-2, the coronavirus causing COVID-19, uses its spike protein to invade and infect another individual, or the host. Antibodies, produced by the host in response, bind to the spike protein to block its action and prevent infection. The researchers, led by those at The University of Texas in Austin, US, isolated the antibody 'SC27' from the plasma donated by four patients. These patients had breakthrough infections, which occur when a vaccinated individual gets infected. The research has been published in the journal Cell Reports Medicine. Over the more than four years since the first case of COVID-19 emerged, SARS-CoV-2 has evolved to acquire certain characteristics which make the virus resistant to vaccines and treatments. The authors said the 'SC27' antibody recognised all these various characterist
The new biomarkers, created by the MRU team, are designed to identify patients at risk of severe Covid-19 in the early stages of infection
In India, 11.9 lakh excess deaths occurred in 2020 during the COVID-19 pandemic, 17 per cent higher compared to 2019, an international study has found. The estimate is about eight times higher than the official COVID-19 deaths in India, and 1.5 times the World Health Organization's estimates, researchers, including those from the University of Oxford, UK, said. Using data of over 7.65 lakh individuals, the study estimated changes in life expectancy at birth, by gender and social group between 2019 and 2020 in India, a country where one-third of global pandemic excess deaths are thought to have occurred, according to the authors. The data was taken from the National Family Health Survey-5 (NFHS-5). The life expectancy in women fell by 3.1 years, while it fell by 2.1 years in men, the authors said. Gender inequalities in healthcare and resource distribution within households could be possible reasons, they said. The patterns contrast with those seen in high-income countries, where .
The funding is part of Project NextGen, a $5 billion initiative led by the Biomedical Advanced Research and Development Authority (BARDA)
The World Health Organisation begins its annual meeting on Monday with government ministers and other top envoys hoping to reinforce global preparedness for the next pandemic in the devastating wake of COVID-19. But the most ambitious project, to adopt a pandemic treaty, has been shelved for now after 2 1/2 years of work failed to produce a draft that countries could unite behind by Friday, as originally hoped. WHO Director-General Tedros Adhanom Ghebreyesus insists it's not a failure and the World Health Assembly this week can still plot the way forward. When diplomats, health officials and activists were still attempting to produce a draft treaty, he predicted the assembly could be one of the most significant in WHO's 76-year history. Not anymore. WHO officials and others have been eager to build on the momentum of concern from the coronavirus pandemic, with the risk that the more it fades into history, the less the public and policymakers will be interested in preparing for a
An unusual form of cell death could lead to a Covid patient's lungs suffering extreme damage, potentially resulting in life-threatening conditions such as inflammation and acute respiratory disorders, according to new research. The ability to inhibit this unusual form of cell death -- ferroptosis -- can offer doctors new ways of to treat Covid-19 lung disease, the study suggested. Cell death, where a cell stops functioning, can be natural or could result from causes such as a disease or an injury. The most common form of cell death involves cells "chopping up" the molecules inside, researchers explained, adding that this occurs in humans, both when they are ill or are ageing. However, in ferroptosis, the relatively uncommon form of cell death, cells die because their outer fat layers collapse, the researchers at Columbia University, US, said. In this study, they analysed human tissues and collected autopsies of patients who died of respiratory failure caused by Covid-19 infection.
Singapore is seeing a new COVID-19 wave as the authorities recorded more than 25,900 cases from May 5 to 11 even as Health Minister Ong Ye Kung on Saturday advised the wearing of masks again. We are at the beginning part of the wave where it is steadily rising, said Ong. So, I would say the wave should peak in the next two to four weeks, which means between mid- and end of June, The Straits Times newspaper quoted the minister as saying. The Ministry of Health (MOH) said the estimated number of COVID-19 cases in the week of May 5 to 11 rose to 25,900 cases, compared with 13,700 cases in the previous week. The average daily COVID-19 hospitalisations rose to about 250 from 181 the week before. The average daily intensive care unit (ICU) cases remained low at three cases, compared with two cases in the previous week. The MOH said that to protect hospital bed capacity, public hospitals have been asked to reduce their non-urgent elective surgery cases and move suitable patients to ...
In the wake of pharmaceutical giant AstraZeneca admitting in a UK court that its Covid vaccine can cause blood clots in rare cases, a group of doctors on Thursday expressed deep concern over the safety of the Covishield vaccine manufactured by the Serum Institute of India. At a press conference, the doctors, under the banner of the Awaken India Movement (AIM), urged the government to review the science behind all Covid vaccines and audit their commercialisation as well as implementation of active surveillance and monitoring mechanism to ensure vaccine adverse events are identified as early as possible. "The government has wholly ignored the rising number of cases of tragic deaths post-Covid vaccination all the while and continues to promote Covid vaccines as 'safe and effective', without scientific investigation and invoking epidemiology," Dr Tarun Kothari, a radiologist and an activist, said at the press conference. The world is learning about a side effect of the Covid vaccine ...
According to media reports, the Anglo-Swedish drugmaker has previously admitted in court documents that the vaccine causes side-effects such as blood clots and low blood platelet counts
The first scientist to publish a sequence of the COVID-19 virus in China said he was allowed back into his lab after he spent days locked outside, sitting in protest. Zhang Yongzhen wrote in an online post early on Wednesday that authorities had tentatively agreed to allow him and his team to return to his laboratory and continue their research for the time being. Zhang had been staging a sit-in protest outside his lab since the weekend after he and his team were suddenly notified they had to leave their lab, a sign of Beijing's continuing pressure on scientists conducting research on the coronavirus. The Shanghai Public Health Clinical Center previously said Zhang's lab was being renovated and was closed for safety reasons. But Zhang said his team wasn't offered an alternative until after the eviction and the new lab didn't meet safety standards for conducting their research. Zhang's latest difficulty reflects how China has sought to control information related to the virus: An ..
The Congress on Friday claimed that the Modi government was "dragged into" providing free COVID-19 vaccinations on the insistence of the opposition and the Supreme Court, and said it is hard to forget the "extent of the mismanagement" that occurred during the pandemic. Congress general secretary Jairam Ramesh said the BJP has been touting free COVID-19 vaccinations as a big achievement. "The truth is the Modi Sarkar was dragged into doing so by the insistence of the Opposition and the intervention of the Supreme Court. Aap chronology samajhiye: On April 18, 2021, Dr. Manmohan Singh writes to the Prime Minister, urging him to clarify vaccine policy - which until then was chaotic and not systematized - and giving him well-thought out suggestions on how to maximise vaccinations," Ramesh said on X. On April 19, 2021, the Union government announced the "Liberalised Pricing and Accelerated National COVID-19 Vaccination Strategy" which made the vaccination of citizens between 18 and 44 yea
The trials will assess the vaccine's safety, immune response, and efficacy in preventing TB in adults and adolescents. MTBVAC has been developed after research spanning over three decades
JN.1, a new COVID variant, has become dominant in China. A total of 6,653 cases were reported last month
The White House on Monday lifted its COVID-19 testing requirement for those who plan to be in close contact with President Joe Biden, Vice President Kamala Harris and their spouses, bringing to an end the last coronavirus prevention protocol at the White House. The White House said the change aligns its policies with the Centers for Disease Control and Prevention guidance. The agency last week relaxed its recommendation that those who test positive for COVID-19 isolate for five days. Now, the agency says people can return to work or regular activities if their symptoms are mild and improving and it's been a day since they've had a fever. The White House testing protocol was instituted shortly after the pandemic began in 2020 when former President Donald Trump was in the White House. It was further strengthened by Biden's administration when he took office amid the pandemic in January 2021. Both Trump and Biden contracted the virus while in office. Trump required hospitalization afte
These guidelines offer practical advice for individuals and organisations to navigate the complexities of illness, recovery, and preventing transmission
India saw a single-day rise of 105 COVID-19 cases, while the number of active cases of the infection was recorded at 875, the Union health ministry said on Tuesday. A new death due to the viral disease was reported from Punjab in a span of 24 hours, according to the ministry's data updated at 8 am. The number of daily Covid cases was in double digits till December 5, 2023, but it began to rise after the emergence of a new variant of the virus and cold weather conditions. After December 5, the maximum of 841 cases were reported on December 31, 2023, which was 0.2 per cent of the peak number of cases reported in May 2021, official sources said. India has witnessed three Covid waves in the past, with the peak incidence of daily cases and deaths being reported during the Delta wave in April-June 2021. At its peak, 4,14,188 new Covid cases and 3,915 deaths due to the infection were reported on May 7, 2021. Since the pandemic broke out in early 2020, more than 4.5 crore people in India
The viral-vector jabs were also tied to an increased risk of Guillain-Barre syndrome, a neurological disorder in which the immune system mistakenly attacks the peripheral nervous system
India has logged 110 new cases of Covid, while the number of active cases of the infection stood at 893, according to the Union Health Ministry data updated on Monday. No new deaths have been reported in a span of 24 hours, the data updated at 8 am stated. The number of daily cases had dropped to double-digits till December 5, 2023 but cases had begun to increase after emergence of a new variant and cold weather conditions. After December 5, a maximum of 841 new cases were reported on December 31, 2023 which is 0.2 per cent of the peak cases reported in May 2021. India has witnessed three waves of COVID-19 in the past with the peak incidence of daily new cases and deaths being reported during the Delta wave in April-June 2021. At its peak, 4,14,188 new cases and 3,915 deaths were reported on May 7, 2021. Since the pandemic began in early 2020, more than 4.5 crore people have been infected and over 5.3 lakh deaths recorded.
India has logged 123 new cases of Covid, while the number of active cases of the infection stood at 876, according to the Union Health Ministry's data updated on Tuesday. Four new deaths --two from Delhi and one each from Gujarat and Maharashtra-- have been reported in a span of 24 hours, the data updated at 8 am stated. The number of daily cases had dropped to double-digits till December 5, 2023 but cases had begun to increase after emergence of a new variant and cold weather conditions. After December 5, a maximum of 841 new cases were reported on December 31, 2023 which is 0.2 per cent of the peak cases reported in May 2021, official sources said. India has witnessed three waves of COVID-19 in the past with the peak incidence of daily new cases and deaths being reported during the Delta wave in April-June 2021. At its peak, 4,14,188 new cases and 3,915 deaths were reported on May 7, 2021. Since the pandemic began in early 2020, more than 4.5 crore people have been infected and
India has recorded a single-day rise of 74 new COVID-19 infections and the number of active cases of the disease in the country stands at 871, according to Union Health Ministry data on Monday. No new deaths due to the disease were reported in 24 hours, the data updated at 8 am showed. India has witnessed three waves of COVID-19 in the past with the peak incidence of daily new cases and deaths being reported in the delta wave during April-June 2021. At its peak, 414,188 new cases and 3915 deaths were reported on May 7, 2021. Since the pandemic began in early 2020, more than 4.5 crore people have been infected and over 5.3 lakh deaths due to the disease recorded in the country. The number of people who have recuperated from the disease stands at over 4.4 crore, according to the ministry's website. Besides, 220.67 crore doses of COVID-19 vaccines have so far been administered in the country.